Serum magnesium levels in gestational diabetes
Objective: To assess the relation between gestational diabetes and daily magnesium intake and magnesium deficiency in pregnant women with gestational diabetes.
Methods: Fifty-three patients pre-diagnosed as gestational diabetes and 49 healthy pregnant women who were examined at the Endocrinology and Obstetric Outpatiet Clinics from April 2008 to January 2009 were included in the study. Body mass index (BMI) of patients were determined, obstetric characteristic, history of diabetes in the family was investigated and symptoms of magnesium deficiency were assessed. American Food and Nutrition Board’s references were used to assess the nutrition status of patients. HbA1c, serum magnesium and calcium, kidney and liver function tests, amylase levels were measured and complete urine analysis was performed. Data were tested by correlation and multiple linear regression analysis.
Results: Mean age, gravida, parity and body mass index were significantly higher in patient group (p<0.05). The ratio of women who had a body mass index higher than 30 before pregnancy in the gestational diabetes group was 30.2%, and the ratio of those of whose BMI was between 25-29.9 was 50.9%. No significant differences were found between groups in terms of daily magnesium intake and serum magnesium levels (p=0.234, p=0.337, respectively). Daily magnesium intake was significantly higher in patients with nausea and vomiting (p=0.001, p=0.006). No significant difference was found between serum magnesium levels and HbA1c and serum calcium levels (p=0.444, p=0.614, respectively).
Conclusions: Although slight decreases were seen in serum magnesium levels during pregnancy, no differences were found in this study either in daily magnesium intake or serum magnesium levels between pregnant women with gestational diabetes and without gestational diabetes.